Job description Posted 11 November 2021

Analytical Scientist 


12 month contract

£30.50ph (UMB)

Materials Science provides holistic understanding of how structure influences particle and powder properties to design a particle process which optimises drug product processing and performance.

As projects advance through development, materials scientists support project teams by performing laboratory studies, analysing data, from lead optimization up to and including the transfer and industrialization of manufacturing processes to commercial facilities. Your role will be focused on the characterisation of drug substances to support the design, selection and progression of all new drug products developed within GSK’s Pharmaceutical portfolio. This will be based on generation of biopharmaceutics knowledge and material science understanding created using a range of in-vitro analytical methods and physical properties techniques.


• Developing plans and executing laboratory experiments for in-vitro biorelevant measurements of a drug substance or formulation (e.g. kinetic solubility, dissolution, Intrinsic Dissolution Rate, particle imaging and permeability) across multiple projects to generate data to inform R&D decision making

• Work in collaboration with partners (e.g. Pharmaceutical Development, Biopharmaceutics, CMC Analytical) to obtain inputs for predicting and modelling in-vivo product performance.

• Design and perform physical properties analysis of drug substance and drug product when required using a range of analytical techniques, including XRPD, Raman, DSC, TGA, Optical Microscopy

• Ensure appropriate quality activities are performed throughout development including authoring of analytical test results

• Work effectively and collaboratively on multi-disciplinary medicine development teams

• Perform data management and some data interpretation, record results effectively and communicate results in technical reports

• Comply with local regulatory and data integrity requirements, including cGMP and GSK policies and procedures, with high quality and attention to one’s own safety


• BSc in Chemistry, Pharmaceutical Sciences, Materials Science or equivalent

• Effective oral and written communication skills

• Working knowledge of physical and analytical chemistry

• Good time management and team-working skills

• Experience in a lab-based setting


• Experience in in-vitro biorelevant measurements (e.g. solubility/dissolution, HPLC, Intrinsic Dissolution Rate, transfer models, UV Dissolution Imaging) to support oral biopharmaceutics

• Scientific knowledge and understanding of the anatomy/physiology of body, absorption, distribution & metabolism, and integration of biopharmaceutics with formulation design across dosage forms.

• Experience in solid state characterisation techniques